Genetic Changes In The Ebola Virus – Part 1 of 2
Genetic Changes In The Ebola Virus. Genetic changes that have occurred in the Ebola virus over the pattern few decades could make it more difficult for scientists to find ways to attend the deadly pathogen, a new study says. Many of the most promising experimental drugs being developed to fight Ebola bind to and target a section of the virus’s genetic sequence or a protein derived from that genetic sequence. If there are significant changes in Ebola’s genetic sequence, these drugs may not work, the researchers explained. The researchers compared the genetic makeup of the Ebola labour causing the informed outbreak in West Africa with the genetic makeup of strains that caused outbreaks in Africa in 1976 and 1995.
Compared to the older strains, the current strain had changes in about 3 percent of its genetic structure, the consider authors said. The findings were published Jan. 20 online in the journal mBio. “Our work highlights the genetic changes that could affect these sequence-based drugs that were in designed in the early 2000s based on virus strains from outbreaks in 1976 and 1995,” study senior author Gustavo Palacios said in a journal news release.